{"id":88,"date":"2011-04-13T19:56:14","date_gmt":"2011-04-13T17:56:14","guid":{"rendered":"http:\/\/www.awametox.se\/?page_id=88"},"modified":"2016-02-04T19:15:01","modified_gmt":"2016-02-04T18:15:01","slug":"selected-publications-and-lectures-by-alf-claesson","status":"publish","type":"page","link":"https:\/\/awametox.se\/?page_id=88","title":{"rendered":"Selected publications and lectures by Alf Claesson"},"content":{"rendered":"

A Claesson. On the mechanism of paracetamol\u2019s analgesic activity and a note on related NSAID pharmacology. Manuscript published on http:\/\/www.slideshare.net\/aclaesson\/paracetamol-mechanism-on-slide-share<\/a>.<\/p>\n

A Claesson, O Spjuth. On Mechanisms of Reactive Metabolite Formation from Drugs<\/a>. Mini-Rev Med Chem <\/em> 2013, 13<\/strong>, 720-9.<\/p>\n

A Claesson. Increased drug safety – avoiding reactive metabolites. Presentation published 2012 on Slideshare<\/a>.<\/p>\n

Thompson RA, Isin EM, Li Y, Weaver R, Weidolf L, Wilson I, Claesson A, Page K, Dolgos H, Kenna JG. Risk assessment and mitigation strategies for reactive metabolites in drug discovery and development.<\/a> Chem Biol Interact<\/em>. 2010 Nov 11.<\/p>\n

A Claesson. [New analgesics coming. Monoclonal NGF antibody takes the lead].<\/a> In Swedish. L\u00e4kartidningen<\/em>. 2009 Feb 11-17;106(7):430-4. Review.<\/p>\n

Baraznenok IL, Jonsson E, Claesson A. 3-(2,5-Dihydro-1H-pyrrol-2-ylmethoxy)pyridines: synthesis and analgesic activity. Bioorg Med Chem Lett.<\/em> 2005, 15<\/strong>, 1637-40.<\/p>\n

Lead author of textbook: A Claesson, B Danielsson, U Svensson. [Medicinal Chemistry<\/a>]. In Swedish. Apotekarsocieteten 2005 (3rd<\/sup> ed.), 490 pages.<\/p>\n

Lecture \u201cMolecular approaches toward new analgesics\u201d at SMi Conference on Pain Therapeutics<\/em>, London, June 12-13, 2006<\/p>\n

Swahn BM, Edvinsson KM, Kallin E, Larsson U, Berge OG, Molin H, Pelcman B, Claesson A. Two non-racemic preparations of a piperidine-based NMDA antagonist with analgesic activity.<\/a> Bioorg Med Chem<\/em>. 1997, 5<\/strong>(7):1293-9<\/p>\n

S M Hammond, A Claesson, A M Jansson, L-G Larsson, B G Pring, C M Town, B Ekstr\u00f6m. A new class of synthetic antibacterials acting on lipopolysaccharide biosynthesis. Nature<\/em> 1987, 327<\/strong>, 730-2.<\/p>\n

A Claesson, A M Jansson, B G Pring, S M Hammond, B Ekstr\u00f6m. Design and synthesis of peptide derivatives of a 3-deoxy-D-manno-2-octulosonic acid (KDO) analogue as novel antibacterial agents acting on lipopolysaccharide biosynthesis. J. Med. Chem.<\/em> 30<\/strong>, 2309-13 (1987).<\/p>\n

C Sahlberg, A Quader, A Claesson. Synthesis of conjugated dienes by nickel-catalyzed reactions of 1,3-alkadien-2-yl phosphates with Grignard reagents. Tetrahedr. Lett.<\/em> 24<\/strong>, 5137-5138 (1983).<\/p>\n

A Krantz, B Kokel, A Claesson et al. Allenic amines as inactivators of mitochondrial monoamine oxidase. In Kalman (ed.), Drug Action and Design: Mechanism-based Enzyme Inhibitors<\/em>. Elsevier North 1979.<\/p>\n

Donald C. Booth, Thomas W. Phillips, Alf Claesson, Robert M. Silverstein, Gerald N. Lanier and Janet R. West. Aggregation pheromone components of two species of Pissodes weevils (Coleoptera: Curculionidae) Isolation, identification, and field activity<\/a>. J Chem Ecol,<\/em> 1983, 9<\/strong>, 1-12.<\/p>\n

A Krantz,\u00a0 B Kokel, A Claesson, C Sahlberg.\u00a0 An unusually selective photochemical reaction of a flavin<\/a>. J. Org. Chem<\/em>., 1980, 45<\/strong> , 4245\u20134248.<\/p>\n

Christer Sahlberg, Svante B. Ross, Ingrid Fagervall, Anna Lena Ask, Alf Claesson. S<\/strong>ynthesis and monoamine oxidase inhibitory activities of .alpha.-allenic amines in vivo and in vitro. Different activities of two enantiomeric allenes. J. Med. Chem.<\/em>, 1983<\/a>, 26<\/strong> (7), pp 1036\u20131042.<\/p>\n

A Claesson, L-I Olsson. Allenes and acetylenes. 22. Mechanistic aspects of the allene-forming reductions (SN2′ reaction) of chiral propargylic derivatives with hydride reagents<\/a>. J . Am. Chem. Soc.<\/em>, 1979<\/strong>, 101 (24), pp 7302\u20137311.<\/p>\n

\"\"<\/a><\/p>\n

 <\/p>\n","protected":false},"excerpt":{"rendered":"

A Claesson. On the mechanism of paracetamol\u2019s analgesic activity and a note on related NSAID pharmacology. Manuscript published on http:\/\/www.slideshare.net\/aclaesson\/paracetamol-mechanism-on-slide-share. A Claesson, O Spjuth. On Mechanisms of Reactive Metabolite Formation from Drugs. Mini-Rev Med Chem 2013, 13, 720-9. A Claesson. Increased drug safety – avoiding reactive metabolites. Presentation published 2012 on Slideshare. Thompson RA, Isin…<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"open","template":"","meta":{"footnotes":""},"class_list":["post-88","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/awametox.se\/index.php?rest_route=\/wp\/v2\/pages\/88","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/awametox.se\/index.php?rest_route=\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/awametox.se\/index.php?rest_route=\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/awametox.se\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/awametox.se\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=88"}],"version-history":[{"count":17,"href":"https:\/\/awametox.se\/index.php?rest_route=\/wp\/v2\/pages\/88\/revisions"}],"predecessor-version":[{"id":165,"href":"https:\/\/awametox.se\/index.php?rest_route=\/wp\/v2\/pages\/88\/revisions\/165"}],"wp:attachment":[{"href":"https:\/\/awametox.se\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=88"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}